Steroids and derivatives
Medchemexpress LLC Estrone | 53-16-7 | 99.9% | 10 G
Estrone (E1) is a natural estrogenic hormone. It is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the aromatization of androstenedione that occurs in fat cells. It is the main endogenous estrogen in postmenopausal women.
- Natural estrogenic hormone
- Main endogenous estrogen in postmenopausal women
- Solid, white to off-white appearance
- Soluble in DMSO (25 mg/mL)
- Insoluble in water (< 0.1 mg/mL)
- Molecular formula C18H22O2
- Molecular weight 270.37
- Targets estrogen receptor/ERR
- Acts as an endogenous metabolite
Sigma Aldrich Fine Chemicals Biosciences Estrone 3-(beta-D-glucuronide) sodium salt | 15087-01-1 | MFCD00271561 | 25MG
Estrone 3-(beta-D-glucuronide) sodium salt | Purity: >=99% (HPLC) | Mol Wt: 468.47 | 15087-01-1 | MFCD00271561 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Cortisone 21-Acetate | 50-04-4 | MFCD00003609 | 10g
Cortisone 21-Acetate | Purity: 99% | Mol Wt: 402.48 | 50-04-4 | MFCD00003609 | 10g
Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.
- Potent farnesoid X receptor (FXR) antagonist.
- Induces apoptosis in multiple cancer cell lines.
- Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
- Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
- Suitable for biochemical and signaling pathway research applications.
Medchemexpress LLC Estrone sulfate potassium | 1240-04-6 | 99.9% | 388.52 | 50 MG
Estrone sulfate potassium is an inactive endogenous estrogen, convertible to Estrone and Estradiol, and a substrate of the OATP1B3 transporter. It stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, making it applicable to breast cancer-related research.
- Inactive endogenous estrogen
- Can be converted into Estrone and Estradiol
- Substrate of the OATP1B3 transporter
- Stimulates growth of mammary tumors in ovariectomized rats
- Promotes colony formation of dispersed mammary cells
- Useful for breast cancer-related research
Medchemexpress LLC Estrone | 53-16-7 | 99.96% | 1 ML
Estrone (E1) is a natural estrogenic hormone and the main representative of endogenous estrogens. It is produced by several tissues, particularly adipose tissue, through the aromatization of androstenedione in fat cells.
- Purity of 99.96%
- Molecular weight of 270.37
- Chemical formula C18H22O2
- Appears as a solid, white to off-white
- Initial source from microorganisms or as an endogenous metabolite
- Available as a 10 mM, 1 mL solution in DMSO
- Soluble in DMSO (25 mg/mL or 92.47 mM)
- Insoluble in water
- For research use only
eMolecules 50-27-1 | estra-1(10),2,4-triene-3,16,17-triol | Oakwood Chemical | MFCD00668446 | 288.387 | C18H24O3 | 97.000 | CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O | 25mg | 537722281
estra-1(10),2,4-triene-3,16,17-triol | Oakwood Chemical | 50-27-1 | MFCD00668446 | 288.387 | C18H24O3 | 97.000 | CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O | 25mg | 537722281
Cayman Chemical Estrone Steroid Hormones
A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
Cayman Chemical Estrone Steroid Hormones
A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol